The Mnemosyne family of integrated Single-Use-Pump's consist of two parts:
- The re-usable pump non-wetted body containing sensors, electronics, pneumatic controlled pinch valves, communication and 1, 2 or 4 diaphragm (cardiac muscle)
- The single-use, disposable wetted parts consisting of a dome housing (Thorax) to which both the elastic membrane (Pericardium) and the fluid conveying hoses are attached and supplied pre-sterilized in dual film bags.
Integrated products, model names |
Calliope |
Erato |
Thalia |
Polyhymnia |
Cabinet |
Hephaestus U2 |
Hephaestus U2 |
Stand-alone |
Stand-alone |
Layout, number of diaphragms |
dual |
single |
dual |
quadruple |
Diaphragm diameter, mm |
40 |
100 |
150 |
100 |
Stroke Volume, SV, mL/stroke |
2 x 0 - 25 |
1 x 0 - 150 |
2 x 0 - 400 |
4 x 0 - 150 |
Pump capacity, CO range, mL/min |
2 x 0 - 600 |
1 x 0 - 3.000 |
2 x 0 - 6.000 |
4 x 0 - 3.000 |
Hose connection, ID/OD mm |
3/6 |
6-8/10-12 |
8-10/12-15 |
12/18 |
CO = Cardiac Output = (CO = BpM x SV), CO variation = >1:1.000
Physical feature
- No expensive housing materials for traditional steam cleaning requirements
- No mechanical or liquid axle seals, no rotating parts such as electrical motor, coupling or gearboxes
- No ball valves, but controlled pinch valves which do not requiring cleaning
- No pumped media contact to pump body parts – contamination not possible
- Low weight and compact design gives OEM manufactures freedom to design equipment
- Able to pump controlled volumes of any fluid, liquid independent of reasonable inlet and outlet pressure
- Measures accurately the pumped volume, no in-line flow-sensor is needed
- No need for calibration
- All pumps offer infinite turn-down, turn-up scale
Operating features
- Two or more independent pumps able to operate fully controlled in parallel
- Working pressure as much as 5 Bar makes the pump suitable for connection with filtration devices
- Very gentle operation with no rotating parts
- Polyhymnia integrate 4 diaphragm SUPs able to operate combined or independent and hereby useful for concentrate mixing of 4 different fluids with just one pump
- Use 3rd and/or 4th active membranes in Polyhymnia as pulse damper or obtain even higher fluid transfer
- Single-use, low-cost, disposable wetted parts eliminate cleaning issues – just un-pack and exchange
- Self-emptying, drain on inlet and purge on outlet and the pump will convey gas as well
- Self-priming and able to run dry for extended periods
- Zero spallation / shedding of materials as no shear is introduced between the used polymeric materials
- NO silicone nano particles introduced into the fluid stream like from peristaltic pumps
- Max volume per stroke depending on pump size, no minimum volume exist
Programming features - Micro-processor controlled
- Choose one pulse/stroke per day or one pulse per second or any set of pulses in between
- Choose any stroke length and any fraction of a pulse again and again
- Any imaginable operation sequence, cycle for each diaphragm (pulse ramp, pulse train, pulse length, pulse pause, stroke start, stroke length, stroke distance)
- Choose the fluid pressure you want to create – 5 - 6 Bar (depending on supply air pressure)
- Choose the volume you want to pump – (well, according to pump size)
- Real-time information about pumped volume from each diaphragm
- Data acquisition, data logging for each diaphragm
Maintenance features
- No lubrication needed
- No need for strip down pump for cleaning
- Controlled pinch valves - not part of single-use SUP assembly (wetted parts)
- Longevity – diaphragm tested to last +6 month at full stroke length and pulse speed
Installation features
- Single-Use-Pump parts may be part of an all sterile process package with hoses, connectors, etc.
- No tooling needed for SUP cell part replacement – well, a scissor to open the bag!
- Stainless Steel quick release couplings offer easy access for wetted SUP cell replacement - simple "bolt-on"
Data acquisition features
- On-line pressure sensing from build-in sensor
- On-line fluid measurement, metering, the pump measures the volume pumped accurately without external mass flow sensors
Communication features
- Re-usable pump body requires only pressurized air and 24 VDC electrical power
- TCP/IP bus connection and Wi-Fi connection
- All Mnemosyne kids are stand alone and share the same communication module
- Software up-gradable via the Internet