Clio Single-Use-Pump's (SUP) all consist of

The Clio Air-Operated-Diaphragm-Positive-Displacement (AODPD) OneWay direction LASER guided Single-Use-Pump (SUP) cell’s consist of a housing integrating a valve body, a dome, the diaphragm, LASER support and the fluid conveying hoses – all supplied pre-sterilized in dual film bags.

Stand-alone product, model names	CM80	CM100	CM140	CM200	CM300
Layout, number of diaphragms	single	single	single	single	single
Diaphragm diameter, mm	80	100	140	200	300
Stroke Volume, SV, mL / 100 % stroke	50	200	500	1,200	3,000
Cardiac Output, CO range, max mL / min	450	1,500	2,500	9,500	18,000
Beats-per-Minute, BpM, depending on stroke and valve technology used	0 - ~18	0 - ~15	0 - ~10	0 - ~8	0 - ~6
Typical hose connection, ID/OD mm	4/8	8/12	12/18	18/24
SUP cell weight, grams	100	200	300	600	2000
Drive Unit	Clotho	Clotho	Lachesis	Lachesis	Atropos

The basics in operation is copied from the human heart functionality:

• Cardiac Output (CO) = total pumped volume, SUP capacity, ml/min (CO = BpM x SV)
• Beats-per-Minute (BpM) = ranging 0 - 18 BpM, SUP diameter/stroke/volume depending
• Stroke Volume (SV) = programmable from 1 - 100% of SUP cell specification

Physical features

• No expensive housing materials for traditional steam cleaning requirements
• No mechanical axle seals
• No mechanical rotating parts such as electrical motor, coupling or gears
• No moving ball valves, only passive cross-slit silicone valves
• All simple single-use plastic parts – contamination eliminated
• Low weight and compact design give OEM manufactures new freedom to design equipment
• Measures accurately pumped volume, a true Positive Displacement pump – no in-line flow-sensor is needed
• All pumps offer infinite turn-down, turn-up scale of 1:5,000

Operating features

• Volumetric operation precision better than 1% - without any extra flow sensor
• Volume per stroke depending on pump size - no minimum volume exist
• Zero spallation / shedding of membrane materials – low shear forces
• Self-priming from 2 meter suction height
• Standard fluid pressure 1 bar - higher pressure like 3-5 Bar require customized body
• No need for calibration - build in artificial intelligence in Drive Unit
• Pump any fluid - any mixture of liquid and gases
• Dry running for extended periods
• Self-emptying, drain on inlet and purge on outlet as the pump will convey gas as well
• Single-use, disposable wetted parts eliminate cleaning issues – just un-pack and exchange without any tools needed
• Very gently operation with no rotating or rubbing parts - no shear introduced between used polymeric materials parts creating nano size polluting particles
• Working pressure as much as 5 Bar on special models makes the SUP suitable for connection with filtration devices
• Two pumps able to operate fully controlled and in parallel when connected to Clotho-2

Programming features

• Select the continuous volume you want to pump – (well, according to pump size)
• Select the total volume you want to pump
• Select the time you want the pump to operate
• Real-time information about pumping, pumped volume and velocity

Maintenance features

• No tools needed replacing the SUP cell - takes only one minute !
• No lubrication needed
• No need to strip down pump for cleaning
• Longevity - tested to last 0.5 million cycles at 75% CO

Installation features

• Single-Use-Pump cell may easily be part of an all sterile process package
• No tooling needed for Single-Use-Pump cell replacement - one minute operation

Data collection features of the drive Unit

• On-line operation pressure measured by build-in pressure sensor
• On-line Mass-Flow-Control / metering, the pump measures the volume pumped with better than 1% accuracy - without external flow sensors!
• Data acquisition, data logging

Communication features of the drive unit

• OPC-UA allow connection various software, such as DeltaV, Lucullus, DasWare
• Single-Use-Pump cell's need connection to Drive Unit (requires pressurized air, vacuum and 24 VDC electrical power)
• TCP/IP bus connection or Wi-Fi connection
• All Drive Units operate both as stand-alone or combined with other devices
• Clotho and Lachesis and Atropos software are more or less identical and easy up-gradable
• Clotho, Lachesis, Atropos units facilitate a webhost, which allow the user to access the Drive Units via Wi-Fi as well as via IP/TCP from many devices via Ethernet, USB connection (for data export), OPC-UA communication
• Access Clotho, Lachesis, Atropos via build-in touch sensitive display or connect via Wi-Fi a PAD, Smartphone or PC and OPC-UA

Not designed for:

• Viscosity higher than 10,000 centiStoke
• Very abrasive materials for a long time